How does insulin cause animal birth defects?

April 20th, 2009 by admin

I'm doing a research project for government class on Animal Experimentation and I need to know how insulin causes animal birth defects. The project is die in 2 weeks and I have everything done but I still need the answer to this question.

During normal gestation the fetus needs higher levels of nutritions in the blood, that´s why the mother produces a placental hormone called somatomammotropin which has anti-insulin effects reducing the sensibility of the tissues to insuline and thus increasing maternal glucose levels ensuring adequate fetal nutrition. My guess is, since i´m not familiar with birth defects by insulin, Abnormal high levels of insulin during gestation should alter nutrition to the fetus and result in some kind of birth defects. You should investigate the normal function of hormones during gestation and then if there are conditions related to high levels of insulin and how this affects the process.

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2 Responses

  1. Fran

    During normal gestation the fetus needs higher levels of nutritions in the blood, that´s why the mother produces a placental hormone called somatomammotropin which has anti-insulin effects reducing the sensibility of the tissues to insuline and thus increasing maternal glucose levels ensuring adequate fetal nutrition. My guess is, since i´m not familiar with birth defects by insulin, Abnormal high levels of insulin during gestation should alter nutrition to the fetus and result in some kind of birth defects. You should investigate the normal function of hormones during gestation and then if there are conditions related to high levels of insulin and how this affects the process.
    References :

  2. vaughn_nebeker

    try none. even it cloning the drug there none.
    References :

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